Non-antibiotic treatments for bacterial diseases in an era of progressive antibiotic resistance

Non-antibiotic treatments for bacterial diseases in an era of progressive antibiotic resistance

The emergence of multi-drug resistant (MDR) microbial pathogens threatens the very foundation upon which standard antibacterial chemotherapy is based. We must consider non-antibiotic solutions to manage invasive bacterial infections. Transition from antibiotics to non-traditional treatments poses real clinical challenges that will not be easy to solve. Antibiotics will continue to reliably trea...

Bacterial antibiotic resistance pdf

Two page summaries of cross-cutting and bacteriaspecific antibiotic resistance topics. The first section provides context and an overview of antibiotic resistance.Antimicrobial resistance: global report on surveillance. Resistance to antibacterial drugs in selected bacteria of international concern. Previously harmful agents that is known today as antimicrobial resistance. Currently antimicrobi...

antibiotic prescription and bacterial resistance

Bacterial vaccines and antibiotic resistance

Spread of antibiotic resistance is mediated by clonal lineages of bacteria that besides being resistant also possess other properties promoting their success. Some vaccines already in use, such as the pneumococcal conjugate vaccines, have had an effect on these successful clones, but at the same time have allowed for the expansion and resistance evolution of previously minor clones not covered ...

Regulatory RNAs Involved in Bacterial Antibiotic Resistance

An increasing number of RNAs have been recently shown to possess regulatory functions similar to those of proteins. In bacteria, these regulatory RNAs are usually noncoding and are short size (50–500 nts) transcripts that are often referred to as small RNAs (sRNAs) [1,2]. These sRNAs are synthesized under specific environmental conditions and play a major role in the regulation of various cellu...